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ALK5 Inhibitor is a selective and ATP-competitive inhibitor of the TGF-β family type I receptor activin receptor-like kinase (ALK5). It has also been shown that ALK5 can replace Sox2 when reprogramming cells to induced pluripotent stem (iPS) cells.
CAS Number
446859-33-2
Chemical Formula
C17H13N5
Chemical Name
2-(3-(6-methylpyridine-2-yl)-1H-pyrazol-4-yl)-1,5-naphthyridine
Molecular Weight
287.32
QC Specifications
MASS Spec
Mouse ESC culture for toxicity
Shipping Information
on blue ice
Storage
4°C protected from light
Stability
Stable for up to 6 months from date of receipt when stored as directed.
Reference
1. F. Gellibert, et al.; J. Med. Chem. 47, 4494 (2004).
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